{"id":26,"date":"2016-08-11T15:01:18","date_gmt":"2016-08-11T15:01:18","guid":{"rendered":"https:\/\/fs.wp.odu.edu\/epurcell\/?page_id=26"},"modified":"2022-05-11T16:45:58","modified_gmt":"2022-05-11T16:45:58","slug":"publications","status":"publish","type":"page","link":"https:\/\/fs.wp.odu.edu\/epurcell\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p><em><strong>If you don&#8217;t have journal access, I am happy to email you a paper!<\/strong><\/em><\/p>\n<p>Poudel A, Pokhrel A, Oludiran A, Coronado E , Alleyne K, Gilfus M, Gurung R, Adhikari S, <strong>Purcell E<\/strong> Unique features of alarmone metabolism in <em>Clostridioides difficile<\/em>. J. Bacteriology, 2022 Mar 7;e0057521. <a href=\"https:\/\/journals.asm.org\/doi\/10.1128\/jb.00575-21?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub%20%200pubmed\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p><strong>Erin B. Purcell. <\/strong>Second messenger signaling in <em>Clostridioides difficile.<\/em> Current Opinions in Microbiology. 2022 Feb;65:138-144. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S1369527421001661?via%3Dihub\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Poudel A, Oludiran A, S\u00f6zin EB, Casciola M, <strong>Purcell EB<\/strong>, Muratori CM. Growth in a biofilm sensitizes <em>Cutibacterium acnes<\/em> to nanosecond pulsed electric fields<strong>. <\/strong><em>Bioelectrochemistry<\/em> <strong>2021<\/strong> 140:107797. 2021. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1567539421000608?via%3Dihub\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Pokhrel A, Poudel A, Castro KB, Celestine MJ, Oludiran A, Rinehold AJ, Resek AM, Mhanna MA, <strong>Purcell EB. <\/strong>The (p)ppGpp synthetase RSH mediates stationary-phase onset and antibiotic stress survival in <em>Clostridioides difficile<\/em>. J. Bacteriology, 202(19):e00377-20. 2020. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7484180\/\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Oludiran A, Courson DS, Stuart MD, Radwan AR, Poutsma JC, Cotton ML, <strong>Purcell EB<em>. <\/em><\/strong>How oxygen availability affects the antimicrobial efficacy of host defense peptides: lessons learned from studying the copper-binding peptides piscidins 1 and 3. <em> J. Mol. Sci.<\/em>, <em>20<\/em>(21), 5289. 2019. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6862162\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Courson DS, Pokhrel A, Scott C, Madrill M, Rinehold AJ, Tamayo R, Cheney RE, <strong>Purcell EB.<\/strong> Single cell analysis of nutrient regulation of <em>Clostridioides (Clostridium) difficile<\/em> Anaerobe 59:205-211. 2019. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6785396\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Pokhrel A, Poudel A, <strong>Purcell EB<\/strong>. A purification and <em>in vitro<\/em> activity assay for a (p)ppGpp synthetase from <em>Clostridium difficile.<\/em> Journal of Visualized Experiments (141), e58547. 2018. <a href=\"https:\/\/www.jove.com\/t\/58547\/a-purification-vitro-activity-assay-for-p-ppgpp-synthetase-from\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>A Nutrient-Regulated Cyclic Diguanylate Phosphodiesterase Controls <em>Clostridium difficile<\/em> Biofilm and Toxin Production during Stationary Phase. <strong>Purcell EB<\/strong>, McKee RW, Courson DS, Garrett EM, McBride SM, Cheney RE, Tamayo R. Infection and Immunity. 2017. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28652311\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Cyclic diguanylate signaling in Gram-positive bacteria. <strong>Purcell EB<\/strong>, Tamayo R. FEMS Microbiology Review. June 2016. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27354347\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Regulation of Type IV Pili contributes to surface behaviors of historical and epidemic strains of <em>Clostridium difficile<\/em>. <strong>Purcell EB<\/strong>, McKee RW, Bordeleau E, Burrus V, Tamayo R. Journal of Bacteriology. 198(3):565-77. 2015. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26598364\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Cyclic di-GMP riboswitch-regulated type IV pili contribute to aggregation of <em>Clostridium difficile<\/em>.&nbsp; Bordeleau E, <strong>Purcell EB<\/strong>, Lafontaine DA, Fortier LC, Tamayo R, Burrus V. Journal of Bacteriology. 197(5):829-32. 2015. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25512308\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>The second messenger cyclic di-GMP regulates <em>Clostridium difficile <\/em>toxin production by controlling expression of <em>sigD<\/em>. McKee RW, Mangalea MR, <strong>Purcell EB<\/strong>, Borchardt EK, Tamayo R. Journal of Bacteriology. 195(22):5174-85. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24039264\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Identification and characterization of cyclic nucleotide phosphodiesterases. <strong>Purcell EB<\/strong>, Tamayo R. Methods in Molecular Biology. 1016:235-43. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23681583\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Cyclic diguanylate inversely regulates motility and aggregation in <em>Clostridium difficile<\/em>. <strong>Purcell EB<\/strong>, McKee RW, McBride SM, Waters CM, Tamayo R. Journal of Bacteriology. 194(13):3307-16. 2013. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22522894\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>An analysis of the solution structure and signaling mechanism of LovK, a sensor histidine kinase integrating light and redox signals. <strong>Purcell EB<\/strong>, Claudia CA, Palfey BA, Crosson S. Biochemistry. 49(31):6761-70. 2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20593779\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Electronic and protein structural dynamics of a photosensory histidine kinase. Alexandre MT, <strong>Purcell EB<\/strong>, van Grondelle R, Robert B, Kennis JT, Crosson S. Biochemistry. 49(23):4752-9.2010. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20459101\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Photoregulation in prokaryotes. <strong>Purcell EB<\/strong>, Crosson S. Current Opinion in Microbiology. 11(2):168-78. 2008. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18400553\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Two-component signaling systems and cell cycle control in <em>Caulobacter crescentus<\/em>. <strong>Purcell EB<\/strong>, Boutte CC, Crosson S. Advances in Experimental Medicine and Biology. 631:122-30. 2008. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18792685\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>A photosensory two-component system regulates bacterial cell attachment. <strong>Purcell EB<\/strong>, Siegal-Gaskins D, Rawling DC, Fiebig A, Crosson S. Proceedings of the National Academy of Sciences of the United States of America. 104(46):18241-6. 2007. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17986614\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Structure of the redox sensor domain of <em>Azotobacter vinelandii <\/em>NifL at atomic resolution: signaling, dimerization, and mechanism. Key J, Hefti M, <strong>Purcell EB<\/strong>, Moffat K. Biochemistry. 46(12)3614-23. 2007. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17319691\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n<p>Purification and initial characterization of the putative blue light-regulated phosphodiesterase from <em>Escherichia coli<\/em>. Rajagopal S, Key JM, <strong>Purcell EB<\/strong>, Boerema DJ, Moffat K. Photochemistry and Photobiology. 80(3):542-7. 2004. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15453820\" target=\"_blank\" rel=\"noopener\">link<\/a><\/p>\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>If you don&#8217;t have journal access, I am happy to email you a paper! Poudel A, Pokhrel A, Oludiran A, Coronado E , Alleyne K, Gilfus M, Gurung R, Adhikari S, Purcell E Unique features of alarmone metabolism in Clostridioides&#8230; <a class=\"more-link\" href=\"https:\/\/fs.wp.odu.edu\/epurcell\/publications\/\">Continue Reading &rarr;<\/a><\/p>\n","protected":false},"author":3595,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-fullwidth.php","meta":{"footnotes":""},"_links":{"self":[{"href":"https:\/\/fs.wp.odu.edu\/epurcell\/wp-json\/wp\/v2\/pages\/26"}],"collection":[{"href":"https:\/\/fs.wp.odu.edu\/epurcell\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/fs.wp.odu.edu\/epurcell\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/fs.wp.odu.edu\/epurcell\/wp-json\/wp\/v2\/users\/3595"}],"replies":[{"embeddable":true,"href":"https:\/\/fs.wp.odu.edu\/epurcell\/wp-json\/wp\/v2\/comments?post=26"}],"version-history":[{"count":5,"href":"https:\/\/fs.wp.odu.edu\/epurcell\/wp-json\/wp\/v2\/pages\/26\/revisions"}],"predecessor-version":[{"id":123,"href":"https:\/\/fs.wp.odu.edu\/epurcell\/wp-json\/wp\/v2\/pages\/26\/revisions\/123"}],"wp:attachment":[{"href":"https:\/\/fs.wp.odu.edu\/epurcell\/wp-json\/wp\/v2\/media?parent=26"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}