{"id":6057,"date":"2026-03-15T22:29:51","date_gmt":"2026-03-15T22:29:51","guid":{"rendered":"https:\/\/fs.wp.odu.edu\/h1park\/project-nanobot-drug-delivery-5\/"},"modified":"2026-03-16T21:28:23","modified_gmt":"2026-03-16T21:28:23","slug":"project-nanobot-drug-delivery-5","status":"publish","type":"page","link":"https:\/\/fs.wp.odu.edu\/h1park\/project-nanobot-drug-delivery-5\/","title":{"rendered":"Nanobot Vascular Drug Delivery"},"content":{"rendered":"\n\"Nanobot\n
← All Projects<\/a>\ud83d\udd2c Partially by NSF \u2014 and Pending<\/span><\/div>\n\n

Project Overview<\/h2>\n

Lung cancer kills more Americans annually than breast, colon, and prostate cancers combined, yet fewer than 1% of intravenously administered agents reach the tumor, perpetuating severe off-target toxicity. We are currently working on building magnetically guided therapeutic microbots offer a physically distinct solution, but their clinical translation is blocked not by hardware limitations but by the absence of a navigation system capable of operating safely inside a living, breathing, beating human lung. This research will develop and validate a closed-loop adaptive navigation framework–grounded in patient-derived lung cancer imaging, a 150-patient CFD cohort, and 3D-printed vascular \nphantoms–to make intravascular microbot drug delivery clinically viable for pulmonary oncology and extensible to broader vascular-targeted therapies.<\/p>\n\n

Research Objectives<\/h2>\n

[To be Updated]<\/p>\n\n

Team<\/h2>\n

Dr. John H Park, Dr. Winifred M. Lo (EVMS), Dr. Mohamadmahdi Samandari, Dr. Jae H. Lee, Dr. Sujatha Alla, Aditya Nimmagadda, Nagesh Bheesetty\n

Publications<\/h2>\n

[1] Sujhata Alla, Nagesh Bheesetty, and Hyoshin Park. Informative path planning for nano-surgical robot adaptive drug delivery. In IEEE 59th Annual Conference on Information Sciences and Systems (CISS), volume IEEE Information Theory Society, Johns Hopkins University, 2025.\n\n[2] Nagesh Bheesetty, John H. Park, Sujatha Alla, Mike Lee, Mohamadmahdi Samandari, Winifred M. Lo, and Aditya Nimmagadda. Information-theoretic path planning for safe and adaptive nanobot drug delivery. In Journal of Robotics (Revision), 2026.<\/p>\n","protected":false},"excerpt":{"rendered":"

← All Projects\ud83d\udd2c Partially by NSF \u2014 and Pending Project Overview Lung cancer kills more Americans annually than breast, colon, and prostate cancers combined, yet fewer than 1% of intravenously administered agents reach the tumor, perpetuating severe off-target toxicity. We are currently working on building magnetically guided therapeutic microbots offer a physically distinct solution, but…<\/p>\n","protected":false},"author":26990,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/fs.wp.odu.edu\/h1park\/wp-json\/wp\/v2\/pages\/6057"}],"collection":[{"href":"https:\/\/fs.wp.odu.edu\/h1park\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/fs.wp.odu.edu\/h1park\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/fs.wp.odu.edu\/h1park\/wp-json\/wp\/v2\/users\/26990"}],"replies":[{"embeddable":true,"href":"https:\/\/fs.wp.odu.edu\/h1park\/wp-json\/wp\/v2\/comments?post=6057"}],"version-history":[{"count":5,"href":"https:\/\/fs.wp.odu.edu\/h1park\/wp-json\/wp\/v2\/pages\/6057\/revisions"}],"predecessor-version":[{"id":6112,"href":"https:\/\/fs.wp.odu.edu\/h1park\/wp-json\/wp\/v2\/pages\/6057\/revisions\/6112"}],"wp:attachment":[{"href":"https:\/\/fs.wp.odu.edu\/h1park\/wp-json\/wp\/v2\/media?parent=6057"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}